Tenvir- EM Emtricitabine + Tenofovir

What Is Emtricitabine 200mg + Tenofovir 300mg?

Emtricitabine and Tenofovir Disoproxil Fumarate are useful for treating the Human Immunodeficiency Virus (HIV) infection.

Normally, the Human Immunodeficiency Virus is the virus that causes the Acquired Immune Deficiency Syndrome (AIDS).

 Emtricitabine 200mg + Tenofovir 300mg is a suitable option for easily completely preventing the virus in the body.

The combination of the medicines is suitable for the patient in reducing the risk of getting HIV infection.

A combination of these medicines is suitable for easily preventing the high risk in adults and children.

Emtricitabine, and combination with the tenofovir disoproxil fumarate, is widely useful for easily reducing the effect of the virus in the body.

Emtricitabine and tenofovir have been widely called Pre-Exposure Prophylaxis (PrEP) for reducing the risk of HIV.

It is important to understand that the emtricitabine and tenofovir combination is not the cure for AIDS or HIV treatments. 

Doctor would be providing the exact dosage prescription for the medicine. These are significant options for reducing the infection level in the body.

How Does Emtricitabine 200mg + Tenofovir 300mg Work?

Combination of the Emtricitabine 200mg and Tenofovir 300mg works with extensively preventing the HIV viruses from multiplying in the body.

You need to know how does tenofovir work before taking the medicine. The Tenofovir 300mg works by easily reducing the number of viruses in the body.

The medication would easily increase CD4 cells or white blood cells in your blood protect against the infection.

Treating the Human Immunodeficiency Virus (HIV) infection in adults is easier with the Emtricitabine 200mg and Tenofovir 300mg.

Taking the appropriate dosage of the medication is suitable option for easily getting significant results.

Normally, this medicine needs to be taken along with a combination of other anti-HIV medicines.

The emtricitabine is especially the Cytidine Analogue which works with extensively inhibiting the HIV reverse transcriptase.

 It automatically prevents the HIV RNA to DNA transcription. FDA also approved the use of the Emtricitabine recently.

Emtricitabine is the NRTI or Nucleoside Reverse Transcriptase Inhibitor, which has been indicted for the HIV treatments.

These Emtricitabine are also combined with the tenofovir disoproxil to easily reduce the spread of HIV-1 infection.

Cytidine Analogue works by decreasing the amount of HIV in the blood.

Emtricitabine does not cure HIV, but they are effective in decreasing the chance of developing AIDS.

The tenofovir works by easily reducing HIV infection as well as chronic hepatitis B virus infections.

 Tenofovir blocks the reverse transcriptase by reducing the amount of virus spread in the blood.

Normally, Tenofovir will increase CD4 cell count and white blood cells.

Availability at Grant Pharmacy

Emtricitabine and Tenofovir combination therapy are available at Grant Pharmacy, where patients can access high-quality medications and receive personalized care from experienced pharmacists.

How to Use Emtricitabine 200mg + Tenofovir 300mg?

This section is dedicated to the general information regarding common administration methods of the medication. Instructions may vary based on the condition and treatment regimens.

• Take Tenvir-EM 1 time per day, exactly as directed by your healthcare provider.
• The medicine can be taken both before meals and during meals.
• Take the tablet at about the same time each day to support constant treatment.
• In case of use for HIV infection therapy, Tenvir-EM is taken with other antiretroviral medicines.
• In case of use for PrEP therapy, HIV negative status must be confirmed prior to the start of therapy and must be regularly checked, at least 3 times per year according to current U.S. labeling.
• Do not interrupt treatment with Tenvir-EM without consulting a healthcare professional, especially in case of co-existing hepatitis B infection.
• The level of kidney function must be determined before and during therapy; monitoring includes determination of serum creatinine, estimate creatinine clearance, presence of glucose in urine and proteinuria.

Inform your healthcare provider about existing kidney disorders and previous bone problems.

Usage/ Indications

Tenvir-EM is a fixed dose combination containing emtricitabine 200 mg and tenofovir disoproxil fumarate 300 mg. The antiretroviral combination therapy drug is taken together with other antiretroviral drugs for the treatment of HIV-1 infection. Emtricitabine/tenofovir disoproxil fumarate combination is also indicated for pre-exposure prophylaxis (PrEP) of HIV-1 infection in HIV-negative individuals who are at risk of acquiring HIV-1 infection through sexual contacts.

Emtricitabine and tenofovir disoproxil fumarate are nucleoside/nucleotide reverse transcriptase inhibitors that upon entering cell metabolism, inhibit the activity of HIV reverse transcriptase, leading to inhibition of HIV DNA formation and thus slowing down the process of HIV replication. Combination therapy Tenvir-EM is not prescribed as a complete antiretroviral therapy regimen.

Both medications are active against hepatitis B virus; therefore, a test for hepatitis B is required before therapy since discontinuation of emtricitabine/tenofovir therapy in patients with hepatitis B may lead to a significant exacerbation of their condition.

Consult your healthcare provider if symptoms persist or if there are no expected improvements after treatment with this medication.

Patient Education and Counseling

At Grant Pharmacy, we prioritize patient education and counseling to ensure that individuals understand how to take their medications safely and effectively.

Missed Dose:

Take the Emtricitabine 200mg and Tenofovir 300mg medicine as soon as you remember the dosage. When it is time for the next dosage then you need to avoid overdosing with the scheduled dosage.

Go back to your regular schedule to get the best effect. It is important to know that skipping the doses could make making virus to be resistant and increase the risk of infected with the Human Immunodeficiency Virus.

Overdose:

Whether you have overdosed accidentally, then you need to consult emergency medical attention. Seek the doctor for medication attention to avoid any side effects in the blood.

Usual Dosage

Depends on the type of condition, age, body weight, organ functions, and response to treatment.

According to official prescription information, the dosage of the drug commonly recommended for use for the therapy of HIV-1 infection in adults and pediatric patients weighing at least 35 kg is 1 tablet containing emtricitabine 200 mg and tenofovir disoproxil fumarate  the daily dose in HIV-1 PrEP in HIV-negative adults and adolescents weighing at least 35 kg is also 1 tablet per day.

For HIV treatment, for adults with creatinine clearance 30–49 mL/min usually requires twice daily administration of the combination therapy. Fixed dose combination is contraindicated for use if creatinine clearance is less than 30 mL/min or in patients undergoing hemodialysis. In case of use for PrEP, it is contraindicated if estimated creatinine clearance is less than 60 mL/min.

Your doctor will determine the optimal dosage and administration schedule for your condition.

Precautions and Warnings:

Before taking Emtricitabine and tenofovir disoproxil, it is essential to know about the precautions and warnings regarding the medicine.

Emtricitabine 200mg and Tenofovir 300mg will not prevent the spread of the disease.

Whether you have had an infection, then it is best to avoid having unprotected sex and share toothbrushes, drugs, medical needles, or razors.

Seek the doctors immediately to prevent the transmission of HIV during sex.

Talk to your doctor about whether you have an allergic reaction to the Emtricitabine and Tenofovir medicines. Your doctor would be altering the medication for the treatments.

Talk to your doctor about whether you are taking prescription and nonprescription medications, nutritional supplements, or vitamins.

The doctor would be regulating the dosage of the medicine appropriately.

Talk to your doctor whether you are taking any of the medications like

• Antiviral Medication – Sitavig and Zovirax
• Adefovir (Hepsera)
• Cidofovir
• Ganciclovir (Cytovene)
• Valganciclovir (Valcyte)
• Valacyclovir (Valtrex)
• Aspirin
• Ibuprofen (Advil, Motrin)
• Naproxen (Aleve, Naprosyn)
• Gentamicin

Talk to your doctor when you are already taking herbal medicines such as St. John's wort. The doctor recommends not taking the St. John's wort if you are taking Emtricitabine 200mg and Tenofovir 300mg.

Doctors would be prescribing the medicine by analyzing the risks of taking medicines against their benefits.

Knowing about the emtricitabine / tenofovir side effects would be a great option before taking the medicine.

Talk to your doctor if you are pregnant or breastfeeding. Doctors would be suggesting the medicine based on your medication condition. You can also check the emtricitabine/tenofovir cost online from Grant Pharmacy. 

Side effects of Emtricitabine 200mg + Tenofovir 300mg:

Possible side effects of Tenvir-EM therapy are as follows:

• Diarrhea
• Nausea
• Fatigue
• Headache
• Dizziness
• Rash
• Insomnia
• Abnormal dreams
• Discomfort in abdomen

Tenofovir may also cause clinically significant renal impairment and decreases in bone mineral density in certain patients.

Usually, these side effects are transient and mild. Consult your healthcare provider if the side effects are bothering you or do not disappear as soon as they were supposed to.

Storage:

Store Emtricitabine 200mg and Tenofovir 300mg at room temperature, such as 68°F to 77°F or 20°C to 25°C

Keep Emtricitabine and Tenofovir in the container and keep them tightly closed

Keep Emtricitabine 200mg and Tenofovir 300mg out of reach of children

Interactions:

Normally, the interaction of Emtricitabine and Tenofovir, along with other medicines, could be causing side effects in the body. You must not combine the Emtricitabine and Tenofovir with these medicines, such as

• Atazanavir
• Lopinavir
• Didanosine
• Ritonavir
• Cidofovir
• Acyclovir
• Ganciclovir
• Valacyclovir
• Valganciclovir
• Medication that contains Lamivudine
• Adefovir
• Medication that contains Emtricitabine or Tenofovir
• Saquinavir

Consult with your doctor whether you are taking these medicines for various other diseases. The doctor would alternate the dose and duration of the medication as some medicines can interact.

Drugs that impair kidney function or compete with Tenvir-EM regarding its renal elimination may increase emtricitabine or tenofovir blood levels and increase the risk of renal side effects. Concurrent or recent intake of nephrotoxic drugs must therefore be carefully considered.

Tenofovir may increase the concentrations of didanosine and increase its toxicity. Tenofovir may also decrease the concentration of atazanavir unless atazanavir is boosted properly. Certain HIV protease inhibitors and some antiviral agents used in treatment of hepatitis C infection may increase tenofovir concentrations requiring enhanced control for side effects associated with tenofovir therapy.

Combination of Tenvir-EM and other medicinal products containing emtricitabine, tenofovir disoproxil fumarate, or tenofovir alafenamide is unnecessary and should be avoided since it will result in overlapping therapy.

Let your healthcare provider know about the list of medicines that you take currently.

Frequently Asked Questions About Emtricitabine 200mg + Tenofovir 300mg (FAQs)

What Is Emtricitabine 200mg And Tenofovir 300mg? What Is It Used For?

Emtricitabine and Tenofovir involve with combination of medicines belonging to the antiretrovirals group of medicines.

Is Emtricitabine And Tenofovir Safe?

Yes, Emtricitabine 200mg and Tenofovir 300mg safer options to use based on the dosage recommended by the doctor. You need to take the medicine as directed by the doctor and do not skip it.

How Does Emtricitabine 200mg And Tenofovir 300mg Work?

Emtricitabine 200mg and Tenofovir 300mg work by extensively blocking the function of the Enzyme called Reverse Transcriptase. These are quite responsible for replication process of HIV. It is helpful for reducing level of the Human Immunodeficiency Virus in blood.

Does Tenofovir 300mg Affect Fertility?

Emtricitabine and Tenofovir are used as the PrEP so these do not affect male fertility or even the outcome of pregnancy.

Is Emtricitabine And Tenofovir Effective?

Yes, the Emtricitabine and Tenofovir are more effective options for reducing HIV in the body. When you are stopping before the recommended dosage, then it may cause the symptoms to return or worsen.

Medically reviewed by the Grant Pharmacy Pharmacists Medical Team

Medical References

DailyMed – Emtricitabine and Tenofovir Disoproxil Fumarate Tablets, Updated July 1, 2025
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=38e06005-b998-9abb-e063-6294a90a71cb

DailyMed – Emtricitabine and Tenofovir Disoproxil Fumarate Tablets
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c0aa7cb1-ae20-2cbc-e053-2995a90a3284

MedlinePlus – Emtricitabine and Tenofovir
https://medlineplus.gov/druginfo/meds/a612036.html